Integrated Bioimaging Facility Osnabrück (IBiOs)

Core Facility 100 user / year Usage Rules & Regulations

The integrated Bioimaging Facility iBiOs is a core facility within the Center of Cellular Nanoanalytics (CellNanOs), an interdisciplinary Research Center at Osnabrück University. The iBiOs provides access to advanced fluorescence and electron microscopy techniques with highest spatial and temporal resolution. Next to state-of-the-art high-resolution fluorescence imaging techniques, the iBiOs has specialized on live cell single molecule localization microscopy such as PALM/STORM and single molecule tracking as well as single molecule spectroscopy (FLIM, FCS). The iBiOs provides access to cutting-edge techniques such as lattice light-sheet microscopy and develops new nanoparticle based methods such as upconversion microscopy and second harmonic generation microscopy in close collaboration with different research groups at CellNanOs. The EM unit currently applies state-of-the-art 2D scanning and transmission electron microscopy techniques


  • DCV (Deconvolution)
  • Light Sheet
  • LSM - NLO, MP (Non Linear Optics, Multiphoton)
  • Image Analysis
  • FIB-SEM (Focused Ion Beam- Scanning Electron Microscopy)
  • SIM (Structured Illumination Microscopy)
  • SMLM (Single Molecule Localization Microscopy)
  • Cryo-TEM, Cryo-TEM tomography
  • FLIM (Fluorescence Lifetime Imaging Microscopy)
  • Light Sheet, Lattice
  • FCS (Fluorescence Correlation Microscopy)
  • TIRFM (Total Internal Reflection Fluorescence Microscopy)
  • SHG (Second Harmonic Generation)


Dr. Rainer Kurre

Head of Imaging Facility


University of Osnabrück

Center of Cellular Nanoanalytics

Barbarastr. 11

49076 Osnabrück


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