Career

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• Präparation von Proben für die Elektronenmikroskopie
• Bedienung und Betreuung von Geräten zur Probenvorbereitung (Ultramikrotomen, Beschichtungsgeräten etc.)
• Bedienung und einfache Wartungsprozesse eines Transmissionselektronenmikroskops
• Einarbeitung und Unterstützung von Nutzer*innen
• Labor Management
• Einfache Bildanalyse

We are seeking a motivated technical assistant (w/m/d) to join the team of Infectious Diseases Imaging Platform (IDIP, www.idip-heidelberg.org) at the Center for Integrative Infectious Disease Research (CIID, https://ciid-heidelberg.de/), University Hospital Heidelberg, Germany. The successful candidate will support the high-end imaging infrastructure for infectious diseases research and advanced training in pathogen imaging. The technical assistant will be involved in the ongoing research projects that among others aim to develop improved SARS-CoV-2 diagnostic and drug screening assays. Work under enhanced biosafety containment level 2 and 3 (BSL-2 and 3) is planned

A full-time Scientist position is available from August on at the CRFS in the Light Microscopy Facility (LMF). The candidate will work in the LMF at the DZNE in Bonn and will strongly interact with scientists and other core facilities. The LMF is a core facility for scientists, which maintains a variety of up-to-date light microscope setups. The main aim of the facility is to train scientists on various light microscope setups, to support them in establishing their required experimental procedures on the setups, and to develop new techniques/setups for applied light microscopy.

We are seeking a highly enthusiastic candidate with skills in the application of super resolution microscopy technologies in life science research. The position will involve a variety of tasks including but not limited to:

• Providing support in the application of super-resolution microscopy in life science research with particular focus on the application of the MINFLUX technology
• Supporting users with project design, sample preparation and data acquisition across different institutions on campus
• Interpreting images and scientific results in collaboration with users to propose and perform subsequent experiments and procedures
• Serving on a MINFLUX Review Panel to review the feasibility and technical justification of project proposals
• Developing and modifying standard protocols for training sessions
• Executing regular maintenance of the relevant instrumentation. Developing and modifying maintenance protocols on an ongoing basis. Interpreting quality control information and initiating repairs if necessary. Documenting all equipment service.
• Testing / benchmarking commercial and academic workflows and reagents in the field of super resolution microscopy
• Developing and optimizing new super resolution methods tailored to research questions addressed by the users
• Organizing workshops and courses tailored to the needs of the super-resolution community
• Contributing to and building on corporate relationships with vendors in the field

The Imaging & Optics Facility of ISTA provides ‘state of the art‘ Microscopy Application and Flow Cytometry services, as well as assistance in Image Analysis and custom Optical Development solutions. We are enlarging our team and are searching for a full time Microscopy Expert.

• Support of overall facility operation
• Assist in trainings, teaching, technical workshops and outreach
• Optimize and perform quality monitoring and system performance checks
• Support and development of advanced quantitative microscopy-based workflows & data handling (FLIM, FRAP, TIRF, multiphoton, Spinning Disk, Light-Sheet, Super Resolution)
• Operation and support of Fluorescence Assisted Cell Sorting (FACS)
• Participate in image analysis projects and support research projects by providing microscopyservices on a high-end level

The FMP Cellular Imaging Facility supports over 100 researchers with advanced light and electron microscopy technology, develops new imaging techniques for studying living and fixed cells, small organisms and tissue organization. In order to visualize proteins and membranes at the nanoscale we continuously improve our super-resolution microscopes, develop correlative light and electron microscopy to study dynamic processes in the nanometer range and measure molecular interactions by means of Förster resonance energy transfer (FRET). We apply our technologies to own research questions focusing on paracellular barriers, mitochondria and neuronal synapses. The FMP Cellular Imaging Facility is offering a Staff Microscopy Assistant position on technician/BSc./Engineer level.

The European Molecular Biology Laboratory (EMBL), one of the highest ranked scientific research organisations worldwide, has recently opened its new imaging service facility at EMBL Heidelberg campus, the EMBL Imaging Centre (EMBL IC) which has the mission to make the latest imaging technologies available as quickly as possible to a broad, international user community of researchers from academia to industry.

The EMBL IC is looking for an Administrator to join our team to support us and our users. You will work within a vibrant service facility welcoming scientists from all over the world.

Your role

The Administrator provides a wide range of administrative support for all activities of the EMBL IC. The successful candidate will act as the main point of contact in the EMBL IC to the facility staff and our users and will need strong interpersonal skills, a high level of accuracy and the ability to prioritise tasks as well as multitask.

We are looking for a Custom Light Microscopy Developer and / or Biophysicist to support the Advanced Imaging Facility (AIF)

The AIF provides researchers at MPI-CBG with access to high-end microscopy and biophysics imaging techniques that may not yet be commercially available. Recent microscopes provided by the facility include a custom built lattice lightsheet microscope, a large volume imaging microscope and several optical tweezer setups. To ensure MPI-CBG provides its researchers access to the latest innovations in biological and biophysical imaging, the AIF scouts for emerging technologies, builds and maintains advanced light and biophysical microscopy setups, and supports scientists by developing customized solutions.

Job Description

To further strengthen the MPI-CBG’s focus on innovative imaging technologies we are seeking a highly motivated and service-oriented microscopy and / or biophysicist specialist who will become part of the AIF team supporting imaging and biophysics projects spanning all scales from molecular processes and biophysical measurements to the development of entire organs and organisms.

IRB Barcelona is seeking a Postdoctoral Researcher to work at the Colorectal Cancer Laboratory directed by Dr. Eduard Batlle in a joint project with the Advanced Digital Microscopy Facility lead by Dr. Julien Colombelli, as part of the international consortium MACH3CANCER (mach3cancer.org). The project is funded by CRUK and AECC, (reference GEACC19006BAT from the Accelerator Awards of the ‘Fundación de la Asociación Española contra el Cancer (FAECC)’).

The project aims to develop and apply high-throughput 3D live imaging technology that will contribute to the understanding of how cancer cells behave in complex 3D structures and will enable robust interrogation of responses to cancer therapy with single cell resolution. Screens will include longitudinal live cell imaging assays and use sophisticated phenotypic endpoints – with the potential to link to and inform subsequent single cell genomic and proteomic analysis. New, modular, open source, high content analysis (HCA) instrumentation and software tools are currently being developed to address the imaging challenges associated with 3D cell cultures and organoids. In particular, an Oblique Plane Microscope for live-cell High-Content Analysis (HCA-OPM) of patient-derived organoids, based on lightsheet illumination, is being implemented at IRB Barcelona by the inventors of OPM at Imperial College, based on their most recent prototype (see dOPM by Sparks et al: https://doi.org/10.1364/BOE.409781), and will be a central resource to the project, in combination with other High-throughput screening resources (e.g. the LIPSI HTS confocal microscope recently installed at IRB Barcelona). Altogether, this will lead to enhanced understanding of the mechanisms of drug resistance and more effective high content screens for new therapies.

The Leibniz Centre for Photonics in Infection Research (LPI, http://lpi-jena.de) is a project of the National Roadmap for Research Infrastructures of the Federal Ministry of Education and Research (BMBF). As one of the supporting institutions of the LPI, the Leibniz Institute of Photonic Technologies (Leibniz-IPHT, https://www.leibniz-ipht.de/) is looking to recruit a Postdoctoral Research Assistant (f/m/d). The position is full-time and limited to November 30, 2023. An extension might be sought upon suitability. The LPI is being established by a consortium of four supporting institutions (Leibniz-HKI, Leibniz-IPHT, FSU Jena, Universitätsklinikum Jena). In future, it will combine photonic technologies with infection research and thus contribute to the development of new methods for diagnosis, monitoring and therapy for human medicine. Research results will be transferred to clinical practice along the entire value chain. The LPI’s research programme is divided into basic technologies, in which the four supporting institutions jointly address various scientific and technological focal points in an interdisciplinary approach. As a user-open translational infrastructure, LPI makes newly developed demonstrators and methods available to external partners within the framework of joint projects.

The position to be filled comprises the development, the set-up and testing of new microscopy methods for imaging in tissues.

Your tasks

• Development of a high-resolution (STED-based) microscopy system to be used with adaptive optics for three-dimensional image acquisition in tissues. The adaptive optics will be using machine learning and will be feedback based.

• Development of a combination of STED and image scanning microscopy (ISM) for imaging at high isotropic resolution.

Your tasks: Pandemic Forecasting Based on Mathematical Models and Machine Learning

We aim to generate models capable of predicting the SARS/COV2 pandemic load based on parameters of mathematical models. The forecast includes the expected cases being sent to hospital and the need for intensive care units. We already have acquired a good data basis from the previous years to be used for training the models to be developed. We intend to use modern methods such as „robust sparse model discovery (E-SINDy)“ to identify suitable models.

The implementation should be done in a modern performant computer language such as Julia, but Python or Matlab are alternative options. CUDA-based acceleration of calculations based on these models would be good.

Within the scope of this work it is possible to obtain a PhD at the Friedrich-Schiller-Universität Jena.

Job description

The management of image data is a particular challenge in everyday research due to the complexity and often also the size of these data. Within the framework of the DFG-funded project “I3D:bio – Information Infrastructures for Image Data Management”, we will establish an infrastructure that offers services based on OMERO. OMERO is an open-source platform for the vizualisation, management and processing of scientific image data. Within the framework of I3D:bio, target group-oriented and user-oriented instructions for the use of OMERO as a central resource will be made available, as well as tools for the annotation of image data with controlled vocabularies.

Your tasks

At CAi you will be responsible for the deployment of FAIR image data management practices to the German bioimaging research community, including I3D:bio-standard procedures for the installation and operation of OMERO image databases, the deployment of user-friendly data annotation tools. You will contribute to increase the adoption of metadata standards aligned with international initiatives, to deliver support for data deposition in public repositories for bioimage data and help to establish an OMERO-based database for metrology data for the quality control of microscopy systems.

Our requirements

• a master degree in biological sciences, bioinformatics or related fields, PhD desirable
• prior experience with the application of light microscopy and the use of OMERO is essential
• excellent communication skills in an interdisciplinary environment, teamwork, flexibility, strong organizational skills and readiness to travel are expected

The pay scale grouping will be, depending on the personal qualification of the applicant, up to pay grade 13 TV-L.

An der Universität Bielefeld erhalten Sie die besondere Gelegenheit, an dem Aufbau eines neuen universitätsmedizinischen Forschungsstandorts mitzuwirken. In den nächsten Jahren soll im Kontext des Aufbaus der Medizinischen Fakultät OWL zur Unterstützung der Forschung eine zentrale Core Facility (CF) für Mikroskopie und Bildgebung aufgebaut werden. Sie unterstützen die laufende Konzeptionierung und den Aufbau dieser fächerübergreifend genutzten und ständig weiterzuentwickelnden Einheit. Zunächst ist die Realisierung einer sich im Aufbau befindlichen Einrichtung geplant. Im Zeithorizont von acht bis zehn Jahren soll eine umfangreiche CF in einem neu zu errichtenden Gebäude entstehen. Es erwartet Sie eine spannende und verantwortungsvolle Tätigkeit in der Konzeptionierung und dem Aufbau dieser CF sowie in der Beratung und Unterstützung der Nutzer*innen und Betreuung der Geräte mit dem Betrieb der CF. Zudem besteht die Entwicklungsperspektive, eine Leitungsfunktion im Management der CF zu übernehmen.

Application deadline: January 19, 2022.

The Chair of Tissue Dynamics (Campàs Lab) at the Cluster of Excellence Physics of Life (PoL) offers a position as Research Associate/Postdoc in Physics and Mechanics of Embryonic Development (m/f/x) (subject to personal qualification employees are remunerated according to salary group E 13 TV-L) starting as soon as possible. The position is initially limited to 2 years, with the option to become extended. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz – WissZeitVG). The position offers the chance to obtain further academic qualification.

The Campàs Lab uses interdisciplinary and quantitative approaches to study the physics and mechanics of multicellular systems, especially in developing embryos (https://physics-of-life.tu-dresden.de/en/research/core-groups/campas). We have recently developed novel techniques to quantify and perturb local tissue mechanics using microdroplets. These techniques offer unique opportunities to study physical aspects of multicellular systems. Our lab, hosted at the Max Planck Institute for Cell Biology and Genetics, is part of the Cluster of Excellence PoL (https://physics-of-life.tu-dresden.de/en), which is a new interdisciplinary research center dedicated to Biological Physics and Quantitative Biology in the outstanding Dresden environment.

Application deadline: December 13, 2021.

About Scionics

Scionics Computer Innovation GmbH is an IT software and services company with over 20 years of experience in providing flexible and innovative solutions for scientific research organizations. We are located in Dresden, Germany, a cultural, innovative and green city where we are part of the Biopolis Dresden research campus. This campus includes renowned international research institutions including the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), the Center for Molecular and Cellular Bioengineering (CMCB), and the Technische Universität Dresden. We work closely with these institutions and have a particularly strong long-standing partnership with the MPI-CBG. If you join our company, you will work in a welcoming and informal work environment with an international and open-minded team and access to new technology, exciting projects and the frontier of life-science research.

About the role

We are looking for a highly motivated Senior Bio-Image Analyst to shape, expand and direct the service portfolio of our Scientific Computing Team with regard to state-of-the-art image analysis solutions.

You will act as the leader of our bio-image analysis team and support the needs of wet lab biologists by advising them on appropriate analysis strategies and implementing solutions to help them answer their research questions while considering factors such as usability and integration of solutions into existing infrastructure.

This position provides unique and exciting opportunities to collaborate on multi-disciplinary projects at the interface of biology and physics including optical technology development, computer vision and machine learning.

This full-time, on-site position is based in Dresden, Germany.

We are looking for a postdoctoral fellow in light sheet microscopy/oblique plane microscopy. In this highly collaborative project we will develop and use novel microscopy techniques to cover new grounds in single cell and tissue biology. The lab is located at the department of experimental medical science at Lund University and has extensive collaboration with the Lund bioimaging centre.

Application deadline: October 31st, 2021

The Max Perutz Labs are committed to elucidating the mechanisms underlying fundamental biomedical processes by analyzing and reconstituting them across spatial and temporal scales. The Central Biooptics Facility supports the institute in this mission and comprises state-of-the-art light microscopy equipment. The facility personnel provides a wide portfolio of state-of-the-art services to Max Perutz labs scientists, including advice on experimental design and data analysis, training as well as maintenance of all 15 currently offered high-end microscope systems. The facility is seeking to expand its team with a postdoc-level person experienced in superresolution microscopy, who will play a key role in the institute’s research endeavors.

In the frame of ARISE (Career Accelerator for Research Infrastructure Scientists) programme, the European Molecular Biology Laboratory (EMBL) is looking for experienced professionals with a background in the fields of computation engineering and data sciences/ imaging and optical engineering/ mechanical engineering or molecular biotechnology, eager to develop novel technologies for life sciences and get trained to operate life science research infrastructures of tomorrow.

The programme receives funding from Horizon 2020 under the Marie Skłodowska-Curie action COFUND (grant agreement No 945405).

EMBL and Marie Skłodowska-Curie Action Cofund are now offering 20 three-year Fellowships to work on method or technology development of your choice which will have a potential to be provided as a service to external life science researchers get trained in operation and management of research infrastructures and service provision.

The training will cover the topics of planning and providing services, managing operation of the research infrastructure, financial management, staff management, innovation and collaboration with industry, strategic planning, understanding science policy and funding system, etc. More details are presented on the ARISE website.

Sites: Europe (Barcelona, Grenoble, Hamburg, Heidelberg, Hinxton, or Rome)

Application deadline: November 30th, 2021

The CECAD Imaging facility is recruiting a highly motivated candidate for image processing and software integration. The facility provides a variety of modern light microscopes and supports life scientists with all aspects related to their imaging projects, including: design of imaging experiments, image processing, visualization and analysis. Furthermore, the facility provides access to all necessary infrastructure, including data storage and management solutions, and access to the HPC cluster provided by the Regional Computing Centre of Cologne. The facility enthusiastically promotes the use of open source software but also holds licenses for commercial image processing software.

Application deadline: August 31st, 2021

The interdisciplinary Research Training Group 2416 “MultiSenses – MultiScales”: Novel approaches to decipher neural processing in multisensory integration” is funded by the Deutsche Forschungsgemeinschaft (GRK 2416) and provides an exciting research and training environment for a cohort of motivated PhD/doctoral candidates. Multisensory processes are fundamental in scaffolding perception, cognition, learning, and behavior. However, the structural and functional architecture that underlies the brain’s ability to seamlessly integrate simultaneous multisensory inputs is poorly understood. Therefore, the goal of the RTG 2416 MultiSenses – MultiScales is to gain a conceptual understanding of the mechanisms that govern crossmodal integration of sensory information at multiple scales. The RTG will provide in-depth expertise in sensory neurobiology, foster the spirit of transdisciplinary collaboration, and offer hands-on training in a variety of cutting-edge techniques.

We aim to train expert individuals that make the transition from cells to systems and behaviour. A coherent, though flexible curriculum will build a solid foundation in the core concepts of neuroscience. Combined with innovative qualification elements, professional skill development and – most importantly – the opportunity to conduct independent research in a nurturing environment, we aim to train neuroscientists that can compete at the highest international level.

Several positions are available, starting October 1, 2021 . Each position is funded for a period of three years. Given the interdisciplinary character of the RTG, candidates from diverse background (including, but not limited to, life sciences, physics, computer sciences, engineering) should apply.

Successful applicants should have an excellent Master’s degree (or equivalent) in any of therelevant fields (e.g., biology, physics, chemistry, medicine, computer science, technical acoustics, bioinformatics, modeling, image analysis, etc.). Fluency in English and a basic understanding / interest in quantitative methods and programming are expected. Applications must be submitted electronically as single .pdf files. The document must comprise a CV, a detailed statement of the candidate’s motivation to join the RTG2416 MultiSenses-MultiScales, transcripts of records summarizing prior academic performance, and names / contact information of two references. Applications should be emailed to m.spehr@sensorik.rwth-aachen.de.

Application Deadline: August 20, 2021.

The Max Planck Institute for Brain Research (MPI for Brain Research) in Frankfurt/Main is a vibrant research institution in the field of basic biological and medical research, with a focus on understanding the functions of the brain’s circuits. Our institute has approx. 300 employees in three research departments and four research groups, as well as several service units.

The state-of-the-art imaging facility strongly supports the scientists in the institute with high expertise and the latest equipment providing various types of modern microscopes and optical methods. In addition to support of the ongoing scientific work at the institute, they are developing and implementing cutting-edge tools in the areas of optics and microscopy to advance the research beyond what is currently possible. Additional information about the facility’s diverse projects and large variety of microscopes are found Here.

Application deadline: June 27th, 2021

A full-time Scientist position is immediately available at the CRFS in the Light Microscopy Facility (LMF). The candidate will work in the LMF at the DZNE in Bonn and will strongly interact with scientists and other core facilities. The LMF is a core facility for scientists, which maintains a variety of up-to-date light microscope setups. The main aim of the facility is to train scientists on various light microscope setups, to support them in establishing their required experimental procedures on the setups, and to develop new techniques/setups for applied light microscopy.

Application deadline: June 26th, 2021

Universität Regensburg, Faculty of Chemistry and Pharmacy, invites applications for a Full Professorship (W3) in Bioimaging:

The position is permanent with a legal status of a civil servant for life (Beamtenverhältnis auf Lebenszeit). Successful applicants (f/m/d), early in their academic careers, are well-experienced and internationally renowned for their research in bioanalytical imaging. Preference is on the development of nanoscale probes and materials, and their application as the basis of innovative preparation techniques for spatially and time-resolved imaging of the highly specific interactions between nanomaterials and biological systems.

Application deadline: June 30th, 2021

The LMF MPI-CBG is one of the largest open access imaging facilities in Germany. It offers 25 advanced imaging systems covering a broad range of different microscopy techniques including: wide-field microscopy, laser-scanning confocal microscopy, two-photon microscopy, spinning disk confocal microscopy, TIRF microscopy, super resolution light microscopy, light sheet microscopy and laser capture microdissection. The facility supports more than 230 users per year who book around 40,000 hours of instrument time annually.

LMF MPI-CBG in Dresden is offering a Research Technician Position.

Application deadline: June 16th, 2021

Seeking an outstanding candidate to fill a postdoctoral position aimed at potentiating the human capital that supports the Advanced Light Microscopy Italian Node of Euro Bioimaging, hosted by the Institute of Biochemistry and Cell Biology, Naples site.

Research theme: Enhancement of the advanced intravital microscopy platform for the study of cell systems, tissues and organs in in vivo mouse models.

Type of activity envisaged: Participation in technical-scientific activities related to research projects / programs related to in vivo analyses of: i) signals generated by fluorescent biosensors in single cells, tissues and organs; ii) tumor progression in mouse models and optochemogenetics.

Ph.D. Fellowship in Bioengineering and Robotics, Curriculum Bionanotechnologies

The processes of Life are naturally dynamic in space and time from the molecular to the organismal level. Among the different imaging techniques, light microscopy is the only one that potentially can work across this full scale of biological organisation. Ideally, light microscopy is able to visualise the inner workings of proteins, protein complexes, organelles, cells, tissues, organs and whole organisms. However, in practice each specific microscopy techniques poses some fundamental limitations in terms of spatiotemporal resolutions/ranges, labelling, invasiveness, and information contents. The core research of our group (Molecular Microscopy and Spectroscopy, MMS) is the design, development, and validation of novel optical, biological and computational tools that allow the modern biologists to peer inside living cells with unprecedented spatiotemporal resolutions/ranges, minimal invasiveness, and augmented information content. This goal can be achieved only by working across many disciplines, from physics to engineering, from computer science to biology.

The PhD student will be fully integrated in this general mission and his/her specific project will be design according to his/her background and skills. Current general projects, among which the candidate will contribute, consist in (i) the implementation of super-resolution laser scanning microscopy techniques (e.g., STED and image-scanning microscopy) for deep- and multi-parameter imaging which leverage a unique class of single-photon detector array recently introduce by our group; (ii) the realisation of single-molecule spectroscopy/imaging/tracking architectures which combines nanometre 3D spatial resolution, high-throughput, and ability to quantitatively study the function and structure of different multi-protein machineries/bio-molecules; (iii) the realisation of a wide-field based microscopy technique for large field-of-view and fast imaging based on non-conventional illumination and detection schemes; (iv) design of computational tools in the context of the above projects for improving the imaging quality, and/or reconstruct the finale images, and/or decodes from the dataset the maximum number of specimen information. The PhD student will work in the realisation of these novel methods in order to investigate the most exciting unresolved question from Life sciences. The PhD student will benefit significantly from the active collaborations of the MMS group with the several computational and photonics groups of the Istituto Italiano di Tecnologia.

Requirements:

The project is extremely multi-disciplinary, and it involves many different aspects. Hence, the position is open to candidate having a Master’s degree in one of the following areas: Physical Science, Computer Science, and Engineering. Ability and motivation to work independently as well as collaboratively in an interdisciplinary team is very important. Good English language speaking and writing skills are required. For Computer Science candidates good coding skills (preferably in Phyton) and knowledge in Artificial Inteligence are important.

How to Apply:

In order to apply for this position, it is mandatory to refer to the procedures administered by the Università degli studi di Genova. Please contact Dr. Giuseppe Vicidomini (giuseppe.vicidomini@iit.it) for information.

Application deadline: June 15th, 2021

Image Analysis Staff Scientist, FMP Berlin working 39 hours/week initially temporary limited to 2 years with the potential of extension and starting as soon as possible.

Job description
Collaboration with researchers in projects that include quantitative image processing, super-resolution microscopy, live-cell imaging and correlative Light and Electron Microscopy

• Development of novel algorithms for image & data processing
• Implementation of automated microscopy acquisition with feedback from analysis
• Collection, Improvement and customization of existing analysis tools
• Training of facility users in Image & Data Analysis tools (ImageJ, Huygens, Imaris, Matlab, Prism)
• Maintenance of Facility IT and microscope infrastructure

Application deadline: May 31st, 2021

Technical Assistant (50%) at LMF, MPI Tübingen

The Light Microscopy and FACS Facility (LMF) at the Max Planck Institute for Developmental Biology in Tübingen professionally supports the institute’s in-house scientifc departments and research groups, consisting of over 400 international colleagues.

The LMF is looking for a Technical Assistant (50%) to start at the earliest date possible as parental leave cover. The part-time position is temporary and will be able to be flled until at least August 2022.

Application deadline: May 27th, 2021